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One even injected the drug, which acts somewhat like a stimulant. Dr. Christopher J. Welsh, a University of Maryland psychiatrist who treated the boy, says the youth told him several of his friends had also tried to crush and snort the mood pill. ...

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Adverse reactions after discontinuation of serotonergic antidepressants, particularly after abrupt discontinuation, include: nausea, sweating, dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e. paresthesia, such as electric shock sensations) tremor, anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures. Prior to initiating treatment with ZOLOFT, screen patients for any personal or family history of bipolar disorder, mania, or hypomania. ...

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Those exceeding 10 mg/kg) thereby increasing the risk of serotonin syndrome in patients receiving higher dosages of the drug either alone or in combination with other serotonergic agents. The manufacturer of selegiline recommends avoiding concurrent selegiline and SSRI therapy. fluoxetine, paroxetine, sertraline) Although selegiline is a selective MAO-B inhibitor at therapeutic dosages, the drug appears to lose its selectivity for the MAO-B enzyme at higher dosages (e. ...

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